Neurotrophin 3 anticorps (C-Term)

N° du produit ABIN7602834

Cet anticorps Lapin Polyclonal détecte spécifiquement Neurotrophin 3 dans WB. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour Neurotrophin 3 anticorps (C-Term) (ABIN7602834)

Antigène: Neurotrophin 3 (NTF3)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Neurotrophin 3 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Neurotrophin 3 anticorps

Épitope: C-Term

Fonction: Anti-Neurotrophin 3/NTF3 Antibody Picoband®

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-Neurotrophin 3/NTF3 Antibody Picoband® (ABIN7602834). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human Neurotrophin 3/NTF3, which shares 89.3% and 95.3% amino acid (aa) sequence identity with mouse and rat Neurotrophin 3/NTF3, respectively.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
1. Kalcheim, C., Carmeli, C., Rosenthal, A. Neurotrophin 3 is a mitogen for cultured neural crest cells. Proc. Nat. Acad. Sci. 89: 1661-1665, 1992. 2. Ma, L., Harada, T., Harada, C., Romero, M., Hebert, J. M., McConnell, S. K., Parada, L. F. Neurotrophin-3 is required for appropriate establishment of thalamocortical connections. Neuron 36: 623-634, 2002. 3. Ozcelik, T., Rosenthal, A., Francke, U. Chromosomal mapping of brain-derived neurotrophic factor and neurotrophin-3 genes in man and mouse. Genomics 10: 569-575, 1991.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Détails sur Neurotrophin 3

Antigène: Neurotrophin 3 (NTF3)

Autre désignation: NTF3

Sujet:

Synonyms: Glutathione S-transferase Mu 3, GST class-mu 3, GSTM3-3, hGSTM3-3, GSTM3, GST5,

Tissue Specificity: Testis and brain.

Background: The protein encoded by this gene is a member of the neurotrophin family, that controls survival and differentiation of mammalian neurons. This protein is closely related to both nerve growth factor and brain-derived neurotrophic factor. It may be involved in the maintenance of the adult nervous system, and may affect development of neurons in the embryo when it is expressed in human placenta. NTF3-deficient mice generated by gene targeting display severe movement defects of the limbs. The mature peptide of this protein is identical in all mammals examined including human, pig, rat and mouse.

Poids moléculaire: 34 kDa

ID gène: 4908

UniProt: P20783

Pathways: Signalisation RTK, Neurotrophin Signaling Pathway